Article
Aberrant gene expression patterns in placentomes are associated with phenotypically normal and abnormal cattle cloned by somatic cell nuclear transfer.
Physiological genomics - 14 Mar 2008
Everts Robin E, Chavatte-Palmer Pascale, Razzak Anthony, Hue Isabelle, Green Cheryl A, Oliveira Rosane, Vignon Xavier, Rodriguez-Zas Sandra L, Tian X Cindy, Yang Xiangzhong, Renard Jean-Paul, Lewin Harris A
Abstract excerpt
Transcription profiling of placentomes derived from somatic cell nuclear transfer (SCNT, n = 20), in vitro fertilization (IVF, n = 9), and artificial insemination (AI, n = 9) at or near term development was performed to better understand why SCNT and IVF often result in placental defects, hydrops, and large offspring syndrome (LOS). Multivariate analysis of variance was used to distinguish the effects of SCNT,...
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