Article
Distribution of HLA-Dw2 in optic neuritis and multiple sclerosis indicates heterogeneity.
Acta neurologica Scandinavica - 1 Sept 1996
Hillert J, Käll T, Olerup O, Söderström M
Abstract excerpt
UNLABELLED: The human leukocyte antigen (HLA) phenotype Dw2 is known to be increased in multiple sclerosis (MS), but only slightly in optic neuritis (ON). MATERIAL AND METHODS: 127 consecutive patients with unilateral monosymptomatic ON were typed genomically for HLA-DR and -DQ genes. RESULTS: The frequency of HLA-Dw2 among ON patients (47%) was found to be significantly higher than among 250 controls (30%) but...
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