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Article

Novel mutant-enriched sequencing identified high frequency of PIK3CA mutations in pharyngeal cancer.

International journal of cancer - 1 Mar 2008

Qiu Wanglong, Tong Guo-Xia, Manolidis Spiros, Close Lanny G, Assaad Adel M, Su Gloria H

Abstract excerpt

We previously reported 4 PIK3CA mutations in 38 head and neck cancer samples, 3 of which were identified in 6 pharyngeal cancer samples. To determine the mutation frequency of PIK3CA in pharyngeal cancer, we studied 24 additional cases of pharyngeal squamous cell carcinoma in this study. Using both direct genomic DNA sequencing and novel mutant-enriched sequencing methods developed specifically for the 3 hot-spot...

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Identifiers

PMID: 17990317
DOI: 10.1002/ijc.23217
PMCID: PMC2792983

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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