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Article

Sharpened cochlear tuning in a mouse with a genetically modified tectorial membrane.

Nature neuroscience - 1 Feb 2007

Russell Ian J, Legan P Kevin, Lukashkina Victoria A, Lukashkin Andrei N, Goodyear Richard J, Richardson Guy P

Abstract excerpt

Frequency tuning in the cochlea is determined by the passive mechanical properties of the basilar membrane and active feedback from the outer hair cells, sensory-effector cells that detect and amplify sound-induced basilar membrane motions. The sensory hair bundles of the outer hair cells are imbedded in the tectorial membrane, a sheet of extracellular matrix that overlies the cochlea's sensory epithelium. The...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 17220887
DOI: 10.1038/nn1828
PMCID: PMC3388746

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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