Article
Polymorphisms in the angiotensinogen gene are associated with carotid intimal-medial thickening in females from a community-based population.
Atherosclerosis - 1 Nov 2001
Chapman C M, Palmer L J, McQuillan B M, Hung J, Burley J, Hunt C, Thompson P L, Beilby J P
Abstract excerpt
BACKGROUND: Polymorphisms within genes of the renin-angiotensin system have been associated with an increased risk of cardiovascular disease. We investigated the association of polymorphisms in the angiotensinogen (AGT) and angiotensin II receptor type 1 (AGTR1) genes with increased intima-media thickness (IMT) and the presence of plaques in carotid arteries. METHODS: Subjects (1111) from the Perth Carotid...
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