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Article

Cardiac and Carotid Markers Link With Accelerated Brain Atrophy: The AGES-Reykjavik Study (Age, Gene/Environment Susceptibility-Reykjavik).

Arteriosclerosis, thrombosis, and vascular biology - 1 Nov 2016

Sabayan Behnam, van Buchem Mark A, Sigurdsson Sigurdur, Zhang Qian, Meirelles Osorio, Harris Tamara B, Gudnason Vilmundur, Arai Andrew E, Launer Lenore J

Abstract excerpt

OBJECTIVE: Pathologies in the heart-brain axis might, independently or in combination, accelerate the process of brain parenchymal loss. We aimed to investigate the association of serum N-terminal brain natriuretic peptide (NT-proBNP), as a marker of cardiac dysfunction, and carotid intima media thickness (CIMT), as a marker of carotid atherosclerosis burden, with structural brain changes. APPROACH AND RESULTS:...

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Identifiers

PMID: 27609370
DOI: 10.1161/ATVBAHA.116.308018
PMCID: PMC5310810

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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