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Article

hDREF regulates cell proliferation and expression of ribosomal protein genes.

Molecular and cellular biology - 1 Mar 2007

Yamashita Daisuke, Sano Yukako, Adachi Yuka, Okamoto Yuma, Osada Hirotaka, Takahashi Takashi, Yamaguchi Tomohiro, Osumi Takashi, Hirose Fumiko

Abstract excerpt

Although ribosomal proteins (RPs) are essential cellular constituents in all living organisms, mechanisms underlying regulation of their gene expression in mammals remain unclear. We have established that 22 out of 79 human RP genes contain sequences similar to the human DREF (DNA replication-related element-binding factor; hDREF) binding sequence (hDRE) within 200-bp regions upstream of their transcriptional...

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Share to Cell Proliferation
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Deletion

Share to Gene Expression Regulation

Share to Promoter Regions, Genetic

Share to Regulatory Elements, Transcriptional

Share to Ribosomal Proteins

Share to Transcription, Genetic

Source

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Identifiers

PMID: 17220279
DOI: 10.1128/MCB.01462-06
PMCID: PMC1820502

Genes

RPS6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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