Article
Ribosomal protein S6 is highly expressed in non-Hodgkin lymphoma and associates with mRNA containing a 5' terminal oligopyrimidine tract.
Oncogene - 31 Mar 2011
Hagner P R, Mazan-Mamczarz K, Dai B, Balzer E M, Corl S, Martin S S, Zhao X F, Gartenhaus R B
Abstract excerpt
The molecular mechanism(s) linking tumorigenesis and morphological alterations in the nucleolus are presently coming into focus. The nucleolus is the cellular organelle in which the formation of ribosomal subunits occurs. Ribosomal biogenesis occurs through the transcription of ribosomal RNA (rRNA), rRNA processing and production of ribosomal proteins. An error in any of these processes may lead to deregulated...
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