Article
Lung cancer susceptibility among atomic bomb survivors in relation to CA repeat number polymorphism of epidermal growth factor receptor gene and radiation dose.
Carcinogenesis - 1 Dec 2009
Yoshida Kengo, Nakachi Kei, Imai Kazue, Cologne John B, Niwa Yasuharu, Kusunoki Yoichiro, Hayashi Tomonori
Abstract excerpt
Lung cancer is a leading cause of cancer death worldwide. Prevention could be improved by identifying susceptible individuals as well as improving understanding of interactions between genes and etiological environmental agents, including radiation exposure. The epidermal growth factor receptor (EGFR)-signaling pathway, regulating cellular radiation sensitivity, is an oncogenic cascade involved in lung cancer,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
