Article
Association of epidermal growth factor receptor (EGFR) gene polymorphism with lung cancer risk: a systematic review.
Journal of receptor and signal transduction research - 1 Oct 2014
Feng Xu, Qin Jia-Jin, Zheng Bao-Shi, Huang Liu-Liu, Xie Xiao-Yong, Zhou Hua-Fu
Abstract excerpt
Epidermal growth factor receptor (EGFR) is a member of the tyrosine kinase receptor family, which is thought to be involved in the development of cancer, as the EGFR gene is often amplified, and/or mutated in cancer cells. Lung cancer remains one of the most major causes of morbidity and mortality worldwide, accounting for more deaths than any other cancer cause. Gene polymorphism factor has been reported to be...
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