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Article

Multiple QTLs influence variation in paraoxonase 1 activity in Mexican Americans.

Human biology - 1 Jun 2006

Winnier Deidre A, Rainwater David L, Cole Shelley A, Dyer Thomas D, Blangero John, Maccluer Jean W, Mahaney Michael C

Abstract excerpt

Paraoxonase 1 (PON1), a high-density-lipoprotein-associated enzyme known to protect against cellular damage from toxic agents, may also have antioxidant properties. Although the importance of the influence of the PON1 structural locus on chromosome 7q21-22 for variation in the concentration and activity of the enzyme is well-documented, the contribution of other loci is poorly understood. Based on the recent...

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Source

Identifiers

PMID: 17216806
DOI: 10.1353/hub.2006.0050

Genes

PON1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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