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Article

Sex-specific QTL effects on variation in paraoxonase 1 (PON1) activity in Mexican Americans.

Genetic epidemiology - 1 Jan 2007

Winnier Deidre A, Rainwater David L, Cole Shelley A, Williams Jeff T, Dyer Thomas D, Blangero John, MacCluer Jean W, Mahaney Michael C

Abstract excerpt

Paraoxonase 1 (PON1), a high-density lipoprotein-associated enzyme known to protect against cellular damage from toxic agents, may also have antioxidant properties. PON1 activity levels have been reported to differ by sex in human and animal studies with females exhibiting higher basal levels. We measured PON1 activity frozen serum for 1,406 individuals in over 40 extended pedigrees from the San Antonio Family...

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Source

Identifiers

PMID: 17136774
DOI: 10.1002/gepi.20191

Genes

PON1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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