Article
The Wnt-signaling pathway is not implicated in tumorigenesis of Merkel cell carcinoma.
Journal of cutaneous pathology - 1 Jan 2007
Liu Shuang, Daa Tsutomu, Kashima Kenji, Kondoh Yoshiyuki, Yokoyama Shigeo
Abstract excerpt
BACKGROUND: The Wnt-signaling pathway, involving beta-catenin, apc, and axin, plays a critical role in numerous developmental events. Alterations in the Wnt-signaling pathway have been detected in a wide variety of neoplasms. However, similar aberrations have not been described in Merkel cell car...
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