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Article

No evidence for involvement of beta-catenin and APC in urothelial carcinomas.

International journal of oncology - 1 May 2002

Stoehr Robert, Krieg Rene C, Knuechel Ruth, Hofstaedter Ferdinand, Pilarsky Christian, Zaak Dirk, Schmitt Ruediger, Hartmann Arndt

Abstract excerpt

The wnt pathway plays an important role in embryonal patterning and cell fate determination, involving stabilization of nuclear and cytoplasmic beta-catenin (CTNNB1) mediated by APC, axin, and other proteins. Uncomplexed beta-catenin binds to TCF/LEF transcription factors and activates the expres...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11956582

Genes

APC
CTNNB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11956582-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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