Article
-509C>T polymorphism in the TGF-β1 gene promoter is not associated with susceptibility to and progression of colorectal cancer in Chinese.
Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland - 1 Nov 2010
Qi P, Ruan C-P, Wang H, Zhou F-G, Zhao Y-P, Gu X, Gao C-F
Abstract excerpt
AIM: Colorectal cancer is common, accounting for nearly 10% of all cancers. Transforming growth factor-β1 (TGF-β1) is a pleiotropic cytokine that has been implicated in the pathogenesis of colorectal neoplasia. The most studied -509C>T polymorphism of TGF-β1 gene has been associated with various kinds of cancer. This study investigated the association between this genetic variant and the risk and/or progression...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.