Cytokine gene polymorphisms in multiple sclerosis: a meta-analysis of 45 studies including 7379 cases and 8131 controls.

doi:10.1111/j.1468-1331.2011.03355.x

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Article

Cytokine gene polymorphisms in multiple sclerosis: a meta-analysis of 45 studies including 7379 cases and 8131 controls.

European journal of neurology - 1 Jul 2011

Nikolopoulos G K, Masgala A, Tsiara C, Limitsiou O K, Karnaouri A C, Dimou N L, Bagos P G

Abstract excerpt

Many environmental and genetic factors have been implicated in the development of multiple sclerosis. However, the aetiology has not been clarified yet. Therefore, using a meta-analytic approach, we tried to probe the potential association between various cytokine gene polymorphisms and the occurrence of multiple sclerosis. A comprehensive literature search yielded 45 eligible studies, which involved 7379 cases...

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Cytokines
Genetic Predisposition to Disease
Multiple Sclerosis
Polymorphism, Single Nucleotide

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PMID: 21299734
DOI: 10.1111/j.1468-1331.2011.03355.x

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