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Article

Association of interleukin-10 promoter single nucleotide polymorphisms -819 T/C and -592 A/C with aging.

The journals of gerontology. Series A, Biological sciences and medical sciences - 1 Dec 2005

Okayama Naoko, Hamanaka Yuichiro, Suehiro Yutaka, Hasui Yoshinori, Nakamura Junji, Hinoda Yuji

Abstract excerpt

Increased inflammatory activity is known to accompany aging. Single nucleotide polymorphisms of inflammatory mediator genes might therefore affect the aging process. Relation of eight SNPs (tumor necrosis factor-alpha [TNF-alpha] -1031 T/C, interleukin-10 [IL-10] -819 T/C, IL-1beta -511 C/T, IL-6 -634 C/G, IL-18 -607 A/C, transforming growth factor-beta [TGF-beta] +869 C/T, matrix metalloproteinase-1 [MMP-1]...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16424284
DOI: 10.1093/gerona/60.12.1525

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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