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Article

A mouse model of basal-like breast carcinoma with metaplastic elements.

The Journal of pathology - 1 Mar 2007

McCarthy A, Savage K, Gabriel A, Naceur C, Reis-Filho J S, Ashworth A

Abstract excerpt

Breast cancers arising in carriers of germline BRCA1 mutations frequently have a basal-like phenotype. Basal-like cancers are characterized by high histological grade, central necrotic areas, foci with metaplastic differentiation, lack of hormone receptor and HER2 (ErbB2) expression, and consiste...

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Source

Identifiers

PMID: 17212342
DOI: 10.1002/path.2124

Genes

BRCA1
EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17212342-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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