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Basal-like Breast Cancers: From Pathology to Biology and Back Again

1 Jun 2018

Abstract excerpt

Human breast cancers referred to as "basal-like" are of interest because they lack effective therapies and their biology is poorly understood. The term basal-like derives from studies demonstrating tumor gene expression profiles that include some transcripts characteristic of the basal cells of the normal adult human mammary gland and others associated with a subset of normal luminal cells. Elucidating the...

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PMID: 29874626
DOI: 10.1016/j.stemcr.2018.04.023

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