Article
A phenotypic mouse model of basaloid breast tumors.
PloS one - 1 Jan 2012
Kim Soyoung, Roopra Avtar, Alexander Caroline M
Abstract excerpt
Chemotherapeutic strategies that target basal-like breast tumors are difficult to design without understanding their cellular and molecular basis. Here, we induce tumors in mice by carcinogen administration, creating a phenocopy of tumors with the diagnostic and functional aspects of human triple negative disease (including EGFR expression/lack of erbB, estrogen-independent growth and co-clustering of the...
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