Article
Nuclear repositioning of the <i>VSG</i> promoter during developmental silencing in <i>Trypanosoma brucei</i>
8 Jan 2007
Abstract excerpt
Interphase nuclear repositioning of chromosomes has been implicated in the epigenetic regulation of RNA polymerase (pol) II transcription. However, little is known about the nuclear position-dependent regulation of RNA pol I-transcribed loci. Trypanosoma brucei is an excellent model system to address this question because its two main surface protein genes, procyclin and variant surface glycoprotein (VSG), are...
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