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Article

Bulged residues promote the progression of a loop-loop interaction to a stable and inhibitory antisense-target RNA complex.

Nucleic acids research - 1 Aug 2001

Kolb F A, Westhof E, Ehresmann C, Ehresmann B, Wagner E G, Romby P

Abstract excerpt

In several groups of bacterial plasmids, antisense RNAs regulate copy number through inhibition of replication initiator protein synthesis. These RNAs are characterized by a long hairpin structure interrupted by several unpaired residues or bulged loops. In plasmid R1, the inhibitory complex between the antisense RNA (CopA) and its target mRNA (CopT) is characterized by a four-way junction structure and a...

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Identifiers

PMID: 11470871
DOI: 10.1093/nar/29.15.3145
PMCID: PMC55835

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Bulged residues promote the progression of a loop-loop interaction to a stable and inhibitory antisense-target RNA complex.PMID 11470871Read ↗

Progression of a loop-loop complex to a four-way junction is crucial for the activity of a regulatory antisense RNA.Semantic proximity Read ↗

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