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Article

Depletion of Med10 enhances Wnt and suppresses Nodal signaling during zebrafish embryogenesis.

Developmental biology - 15 Mar 2007

Lin Xueying, Rinaldo Lorenzo, Fazly Ahmed F, Xu Xiaolei

Abstract excerpt

The transcriptional Mediator (MED) is a multiprotein complex that transmits information from transcription factors to RNA polymerase II (PolII) to regulate transcription. At present, the role of distinct MED subunits in general transcription versus transcription stimulated by specific signaling pathways is unclear. By means of positional cloning, we reveal that the zebrafish mutant tennismatch is a hypomorphic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17208216
DOI: 10.1016/j.ydbio.2006.11.034

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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