Article

Angel Wing: a class of alternative splicing regulators in animals

2025-04-22

Abstract excerpt

Alternative splicing (AS) regulates the diversity and level of the proteome. The specificity in AS is in turn regulated by RNA binding proteins, but our understanding of how they act is far from complete. Here we identify the Angel wing (Anw) protein as a novel AS regulator. Loss of Anw in Drosophila disrupts splicing in muscle genes and subsequently muscle function. Based on a mini-gene assay in which Anw and it...

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Literature Corpus work: 560b4543-12f3-5402-a530-a7bad3e02676
DOI: 10.1101/2025.04.20.649734

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