Article
wimp, a dominant maternal-effect mutation, reduces transcription of a specific subset of segmentation genes in Drosophila.
Genes & development - 1 Mar 1991
Parkhurst S M, Ish-Horowicz D
Abstract excerpt
wimp is a dominant maternal-effect mutation that interacts with a specific subset of early-acting maternal and zygotic Drosophila genes. We show that wimp is a change-of-function mutation, allelic to mutations of the 140-kD subunit of RNA polymerase, which causes reduced transcription of interact...
Topics
- Alleles
- Animals
- DNA-Directed RNA Polymerases
- Drosophila
- Female
- Gene Expression Regulation
- Genes
- Genes, Dominant
- Genes, Recessive
- Male
- Mutation
- Phenotype
- Transcription Factors
- Transcription, Genetic