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Article

The DNA glycosylase/lyase ROS1 functions in pruning DNA methylation patterns in Arabidopsis.

Current biology : CB - 9 Jan 2007

Zhu Jianhua, Kapoor Avnish, Sridhar Vaniyambadi V, Agius Fernanda, Zhu Jian-Kang

Abstract excerpt

The Arabidopsis DNA glycosylase/lyase ROS1 participates in active DNA demethylation by a base-excision pathway. ROS1 has been shown to be required for demethylating a transgene promoter. To determine the function of ROS1 in demethylating endogenous loci, we carried out bisulfite-sequencing analysis of several transposons and other genes in the ros1 mutant. In the wild-type, although CpG sites at the majority of...

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Identifiers

PMID: 17208187
DOI: 10.1016/j.cub.2006.10.059

Genes

ROS1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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