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Article

Transgenerational increases in DNA methylation in Arabidopsis plants defective in active DNA demethylation.

Proceedings of the National Academy of Sciences of the United States of America - 28 May 2024

Tang Kai, Zhu Xiaohong, Xie Shaojun, Lang Zhaobo, Zhu Jian-Kang

Abstract excerpt

Spontaneous gain or loss of DNA methylation occurs in plant and animal genomes, and DNA methylation changes can lead to meiotically stable epialleles that generate heritable phenotypic diversity. However, it is unclear whether transgenerational epigenetic stability may be regulated by any cellular factors. Here, we examined spontaneously occurring variations in DNA methylation in wild-type and ros1 mutant...

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Identifiers

PMID: 38768356
DOI: 10.1073/pnas.2320468121
PMCID: PMC11145202

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