Article
Preventing transcriptional gene silencing by active DNA demethylation.
FEBS letters - 31 Oct 2005
Kapoor Avnish, Agius Fernanda, Zhu Jian-Kang
Abstract excerpt
DNA methylation is important for stable transcriptional gene silencing. DNA methyltransferases for de novo as well as maintenance methylation have been well characterized. However, enzymes responsible for active DNA demethylation have been elusive and several reported mechanisms of active demethylation have been controversial. There has been a critical need for genetic analysis in order to firmly establish an in...
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