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Article

ROS1, a repressor of transcriptional gene silencing in Arabidopsis, encodes a DNA glycosylase/lyase.

Cell - 13 Dec 2002

Gong Zhizhong, Morales-Ruiz Teresa, Ariza Rafael R, Roldán-Arjona Teresa, David Lisa, Zhu Jian Kang

Abstract excerpt

Mutations in the Arabidopsis ROS1 locus cause transcriptional silencing of a transgene and a homologous endogenous gene. In the ros1 mutants, the promoter of the silenced loci is hypermethylated, which may be triggered by small RNAs produced from the transgene repeats. The transcriptional silencing in ros1 mutants can be released by the ddm1 mutation or the application of the DNA methylation inhibitor...

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Source

Identifiers

PMID: 12526807
DOI: 10.1016/s0092-8674(02)01133-9

Genes

ROS1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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