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Article

Expression and functional characterization of FOXP3+CD4+ regulatory T cells in ulcerative colitis

21 Dec 2006

Abstract excerpt

BACKGROUND: CD4+CD25+ regulatory T cells (TR) can prevent or treat experimental murine colitis but little is known about their potential role in human inflammatory bowel disease (IBD). FOXP3 is a transcription factor that plays a critical role in the development and function of CD4+CD25+ TR. The aim of this study was to examine the presence and functional characteristics of TR cells in colonic lymphoid tissues in...

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PMID: 17206665
DOI: 10.1002/ibd.20053

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