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Functional characterisation of human CD4+CD25+ regulatory T cells and the transcriptional regulator, FOXP3

2005-01-01

Abstract excerpt

Naturally occurring CD4+CD25+ regulatory T cells are thought to play an essential role in the maintenance of immunological self-tolerance by actively suppressing auto reactive T lymphocytes. Exploitation of these cells could provide novel and effective therapies for the treatment of various clinical diseases, including autoimmune diseases and cancer. However the biology surrounding these cells is complex and there...

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Identifiers and source

Literature Corpus work
78447e05-8dc4-533d-ae3c-0eb7a3159e4a
DOI
10.21954/ou.ro.000101f1
Open publication

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Functional characterisation of human CD4+CD25+ regulatory T cells and the transcriptional regulator, FOXP3DOI 10.21954/ou.ro.000101f1
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