Article
Klotho gene polymorphism and male bone mass.
Calcified tissue international - 1 Jan 2007
Zarrabeitia M T, Hernández J L, Valero C, Zarrabeitia A L, Ortiz F, Gonzalez-Macias J, Riancho J A
Abstract excerpt
The Klotho gene codes for a protein that is thought to influence the homeostasis of several tissues, including bone, as well as the aging process. Although the mechanism of action has not been fully elucidated, some studies in women have associated Klotho allelic variants to bone mineral density (BMD). The objective of this study was to determine the relationship of a common T/G polymorphism, resulting in a...
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