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Article

Klotho gene polymorphisms are associated with osteocalcin levels but not bone density of aged postmenopausal women.

Calcified tissue international - 1 Sept 2005

Mullin B H, Wilson S G, Islam F M A, Calautti M, Dick I M, Devine A, Prince R L

Abstract excerpt

Osteoporosis is known to have a strong genetic basis. It has been proposed that polymorphisms within the KL (klotho) gene have a significant effect on aging, in particular, the osteoblast defect of aging. The association between polymorphisms within this gene and biochemical markers of bone formation and resorption, bone structure, and fracture rates was studied in 1,190 postmenopausal women with a mean age of 75...

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Identifiers

PMID: 16151675
DOI: 10.1007/s00223-004-0291-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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