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Article

Novel functional dissection of the localization-specific roles of budding yeast polo kinase Cdc5p.

Molecular and cellular biology - 1 Nov 2004

Park Jung-Eun, Park Chong J, Sakchaisri Krisada, Karpova Tatiana, Asano Satoshi, McNally James, Sunwoo Yangil, Leem Sun-Hee, Lee Kyung S

Abstract excerpt

Budding yeast polo kinase Cdc5p localizes to the spindle pole body (SPB) and to the bud-neck and plays multiple roles during M-phase progression. To dissect localization-specific mitotic functions of Cdc5p, we tethered a localization-defective N-terminal kinase domain of Cdc5p (Cdc5pDeltaC) to the SPB or to the bud-neck with components specifically localizing to one of these sites and characterized these mutants...

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Identifiers

PMID: 15509790
DOI: 10.1128/MCB.24.22.9873-9886.2004
PMCID: PMC525480

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Source receipt: pubmed, retrieved 7 Sept 2026.

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