Recruitment of NIMA kinase shows that maturation of the S. pombe spindle-pole body occurs over consecutive cell cycles and reveals a role for NIMA in modulating SIN activity.

doi:10.1101/gad.296204

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Article

Recruitment of NIMA kinase shows that maturation of the S. pombe spindle-pole body occurs over consecutive cell cycles and reveals a role for NIMA in modulating SIN activity.

Genes & development - 1 May 2004

Grallert Agnes, Krapp Andrea, Bagley Steve, Simanis Viesturs, Hagan Iain M

Abstract excerpt

Mitotic exit in Saccharomyces cerevisiae and septation in Schizosaccharomyces pombe are regulated by a conserved signaling network called the mitotic exit and septum initiation networks (SIN), respectively. The network is active on one of the two anaphase B spindle-pole bodies (SPBs). Whereas the inherent asymmetry of growth by budding accounts for elements of the asymmetry in S. cerevisiae, it has been unclear...

Topics

Cell Cycle
Centrioles
Genes, Fungal
Models, Biological
Mutation
Schizosaccharomyces
Spindle Apparatus

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PMID: 15132994
DOI: 10.1101/gad.296204
PMCID: PMC406291

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