Article
Saccharomyces cerevisiae Mob1p is required for cytokinesis and mitotic exit.
Molecular and cellular biology - 1 Oct 2001
Luca F C, Mody M, Kurischko C, Roof D M, Giddings T H, Winey M
Abstract excerpt
The Saccharomyces cerevisiae mitotic exit network (MEN) is a conserved set of genes that mediate the transition from mitosis to G(1) by regulating mitotic cyclin degradation and the inactivation of cyclin-dependent kinase (CDK). Here, we demonstrate that, in addition to mitotic exit, S. cerevisiae MEN gene MOB1 is required for cytokinesis and cell separation. The cytokinesis defect was evident in mob1 mutants...
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