Article
A molecular genetic approach to uncovering the differential functions of dopamine D2 receptor isoforms.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2013
Wang Yanyan, Sasaoka Toshikuni, Dang Mai T
Abstract excerpt
Alterations in the activity of the dopamine D2 receptor (D2R) have been implicated in several neurological and psychiatric disorders, including schizophrenia, Parkinson's disease, Huntington's disease, Tourette syndrome, attention-deficit hyperactivity disorder (ADHD), and drug addiction. Two isoforms of D2R, long form (D2LR) and short form (D2SR), have been identified. The specific function of each D2R isoform...
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