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Article

Site-directed mutagenesis of the human dopamine D2 receptor.

European journal of pharmacology - 1 Oct 1992

Mansour A, Meng F, Meador-Woodruff J H, Taylor L P, Civelli O, Akil H

Abstract excerpt

Based on amino acid sequence and computer modeling, two conflicting three-dimensional models of the dopamine D2 receptor have been proposed. One model (Dahl et al., 1991, Proc. Natl. Acad. Sci. USA 88, 8111) suggests that dopamine interacts with aspartate 80 of transmembrane (TM) 2 and asparagine 390 of TM6 with the transmembranes arranged in a clockwise manner, while a second model (Hibert et al., 1991, Mol....

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Identifiers

PMID: 1358663
DOI: 10.1016/0922-4106(92)90129-j

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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