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Article

Association of a single-nucleotide polymorphism in low-density lipoprotein receptor-related protein 5 gene with bone mineral density.

Journal of bone and mineral metabolism - 1 Jan 2004

Urano Tomohiko, Shiraki Masataka, Ezura Yoichi, Fujita Masayo, Sekine Emiko, Hoshino Shinjiro, Hosoi Takayuki, Orimo Hajime, Emi Mitsuru, Ouchi Yasuyoshi, Inoue Satoshi

Abstract excerpt

Low-density lipoprotein receptor-related protein 5 (LRP5) is an important regulator of osteoblast growth and differentiation, affecting peak bone mass in vertebrates. Here, we analyzed whether the LRP5 gene was involved in the etiology of postmenopausal osteoporosis, using association analysis between bone mineral density (BMD) and an LRP5 gene single-nucleotide polymorphism (SNP). Association of an SNP in the...

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Source

Identifiers

PMID: 15221492
DOI: 10.1007/s00774-003-0492-9

Genes

LRP5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Association of a single-nucleotide polymorphism in low-density lipoprotein receptor-related protein 5 gene with bone mineral density.PMID 15221492Read ↗

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