Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clonal and parallel evolution of primary lung cancers and their metastases revealed by molecular dissection of cancer cells.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jan 2007

Takahashi Kenji, Kohno Takashi, Matsumoto Shingo, Nakanishi Yukihiro, Arai Yasuhito, Yamamoto Seiichiro, Fujiwara Toshiyoshi, Tanaka Noriaki, Yokota Jun

Abstract excerpt

PURPOSE: Several models of cancer progression, including clonal evolution, parallel evolution, and same-gene models, have been proposed to date. The purpose of this study is to investigate the authenticity of these models by comparison of accumulated genetic alterations between primary and corres...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Allelic Imbalance
Share to Chromosomes, Human, Pair 11

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Disease Progression

Share to Lung Neoplasms

Share to Microsatellite Repeats

Share to Models, Biological

Share to Models, Genetic

Share to Neoplasm Metastasis

Source

Identifiers

PMID: 17200345
DOI: 10.1158/1078-0432.CCR-06-0659

Genes

EGFR
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17200345-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clonal and parallel evolution of primary lung cancers and their metastases revealed by molecular dissection of cancer cells.PMID 17200345Read ↗

Genetic Trajectory and Clonal Evolution of Multiple Primary Lung Cancer with Lymph Node MetastasisSemantic proximity Read ↗

Genomic Alteration During Metastasis of Lung Adenocarcinoma.Semantic proximity Read ↗

Clonality and prognostic implications of p53 and epidermal growth factor receptor somatic aberrations in multiple primary lung cancers.Semantic proximity Read ↗

Comparison of p53 and epidermal growth factor receptor gene status between primary tumors and lymph node metastases in non-small cell lung cancers.Semantic proximity Read ↗

Genetic Clonality as the Hallmark Driving Evolution of Non-Small Cell Lung CancerSemantic proximity Read ↗

Mutational analysis of multiple lung cancers: Discrimination between primary and metastatic lung cancers by genomic profile.Semantic proximity Read ↗

Bridging the gap between tumor evolution and clonality diagnostics in multiple lung carcinomas.Semantic proximity Read ↗

Genomic heterogeneity of multiple synchronous lung cancers in Chinese population.Semantic proximity Read ↗

Using molecular characteristics to distinguish multiple primary lung cancers and intrapulmonary metastases.Semantic proximity Read ↗

High frequency of clonally related tumors in cases of multiple synchronous lung cancers as revealed by molecular diagnosis.Semantic proximity Read ↗

New aspects of the clinicopathology and genetic profile of metachronous multiple lung cancers.Semantic proximity Read ↗

Timing and Origins of Local and Distant Metastases in Lung Cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.