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Article

Genomic heterogeneity of multiple synchronous lung cancers in Chinese population.

Cancer medicine - 1 Jan 2024

Zhao Lei, Wang Jin, Zhang Yixiang, Wang Peng, Lv Changsheng, Zhao Shilei, Guo Tao, Li Fengzhou, Gu Chundong, Zhu Yuntao

Abstract excerpt

INTRODUCTION: It is clinically challenging to infer the phylogenetic relationship between different tumor lesions of patients with multiple synchronous lung cancers (MSLC), whether these lesions are the result of independently evolved tumor or intrapulmonary metastases. METHODS: We used the Illumina X10 platform to sequence 128 stage I lung cancer samples collected from 64 patients with MSLC. All samples were...

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PMID: 38348924
DOI: 10.1002/cam4.6928
PMCID: PMC10839131

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