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Article

Using molecular characteristics to distinguish multiple primary lung cancers and intrapulmonary metastases.

PeerJ - 1 Jan 2024

Li Zhenhua, Lv Huilai, Zhang Fan, Zhu Ziming, Guo Qiang, Wang Mingbo, Huang Chao, Guo Lijie, Meng Fanfei, Tian Ziqiang

Abstract excerpt

Objectives: Multiple lung cancers may present as multiple primary lung cancers (MPLC) or intrapulmonary metastasis (IPM) with variations in clinical stage, treatment, and prognosis. However, the existing differentiation criteria based on histology do not fully meet the clinical needs. Next-generation sequencing (NGS) may play an important role in assisting the identification of different pathologies. Here, we...

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High-Throughput Nucleotide Sequencing
Lung
Lung Neoplasms
Mutation
Neoplasms, Multiple Primary

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 38313018
DOI: 10.7717/peerj.16808
PMCID: PMC10838092

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