Article
Overproduction of collagen and diminished SOCS1 expression are causally linked in fibroblasts from idiopathic pulmonary fibrosis.
Biochemical and biophysical research communications - 23 Feb 2007
Shoda Hiroyasu, Yokoyama Akihito, Nishino Ryouhei, Nakashima Taku, Ishikawa Nobuhisa, Haruta Yoshinori, Hattori Noboru, Naka Tetsuji, Kohno Nobuoki
Abstract excerpt
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and often fatal pulmonary disorder, and its pathology is characterized by parenchymal fibrosis. To investigate the characteristics of fibroblasts in IPF, we obtained eight fibroblast cell lines from lungs with IPF and eight lines from...
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