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Article

A locus control region at -12 kb of the tyrosinase gene.

The EMBO journal - 15 Nov 1996

Montoliu L, Umland T, Schütz G

Abstract excerpt

We have shown previously that the tyrosinase gene encompassed in a 250 kb yeast artificial chromosome (YAC) is expressed faithfully in transgenic mice. To define the sequences important for this qualitatively and quantitatively correct expression pattern, we have generated transgenic mice with YACs carrying several deletions in the mouse tyrosinase locus. In particular, we wanted to address the in vivo relevance...

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Identifiers

PMID: 8947025
PMCID: PMC452424

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