Article
Association of a TNAP haplotype with ankylosing spondylitis.
Arthritis and rheumatism - 1 Jan 2007
Tsui Hing Wo, Inman Robert D, Reveille John D, Tsui Florence W L
Abstract excerpt
OBJECTIVE: To use a candidate gene approach to the identification of genetic markers that are significantly associated with ankylosing spondylitis (AS). METHODS: We genotyped 201 multiplex AS families with 1 exonic and 5 intronic single-nucleotide polymorphisms (SNPs) in TNAP, the gene that encodes tissue-nonspecific alkaline phosphatase, and performed family-based association analyses. RESULTS: In our cohort of...
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