Article
The association of LRP5 gene polymorphisms with ankylosing spondylitis in a Chinese Han population.
The Journal of rheumatology - 1 Dec 2011
Liu Jianmin, Zhou Xiaoyan, Shan Zhenxing, Yang Jiguo, Yang Qingrui, Cui Yazhou, Han Jinxiang
Abstract excerpt
OBJECTIVE: To clarify the association between polymorphisms of low-density lipoprotein receptor-related protein 5 (LRP5) with ankylosing spondylitis (AS) in a Chinese Han population. METHODS: Sixteen patients with AS were recruited for preliminary screening through gene sequencing. Then 14 single-nucleotide polymorphisms (SNP) of LRP5 were followed up in 296 patients and 170 controls. RESULTS: Sequencing the LRP5...
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