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Article

Association of an ERAP1 ERAP2 haplotype with familial ankylosing spondylitis.

Annals of the rheumatic diseases - 1 Apr 2010

Tsui Florence W L, Haroon Nigil, Reveille John D, Rahman Proton, Chiu Basil, Tsui Hing Wo, Inman Robert D

Abstract excerpt

OBJECTIVES: To assess whether there is excess transmission of alleles from the ERAP1 ERAP2 locus in families with ankylosing spondylitis (AS). METHODS: 199 multiplex families with AS with four non-synonymous single nucleotide polymorphisms (SNPs), three in the endoplasmic reticulum aminopeptidase 1 (ERAP1) gene (rs27044, rs10050860 and rs30187) and one in the endoplasmic reticulum aminopeptidase 2 (ERAP2) gene...

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Share to Aged
Share to Aminopeptidases
Share to Genetic Predisposition to Disease
Share to Genotype
Share to Haplotypes
Share to Minor Histocompatibility Antigens
Share to Polymorphism, Single Nucleotide
Share to Spondylitis, Ankylosing

Source

Identifiers

PMID: 19433412
DOI: 10.1136/ard.2008.103804

Genes

ERAP1
ERAP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Click a neighbor to travelStep 1 · 12 closest

Association of an ERAP1 ERAP2 haplotype with familial ankylosing spondylitis.PMID 19433412Read ↗

ERAP1 association with ankylosing spondylitis is attributable to common genotypes rather than rare haplotype combinations.Semantic proximity Read ↗

Association of a specific ERAP1/ARTS1 haplotype with disease susceptibility in ankylosing spondylitis.Semantic proximity Read ↗

Associations between ERAP1 polymorphisms and ankylosing spondylitis susceptibility: a meta-analysis.Semantic proximity Read ↗

Associations between ERAP1 polymorphisms and susceptibility to ankylosing spondylitis: a meta-analysis.Semantic proximity Read ↗

ERAP1 polymorphisms and haplotypes are associated with ankylosing spondylitis susceptibility and functional severity in a Spanish population.Semantic proximity Read ↗

Associations between ERAP1 polymorphisms and ankylosing spondylitis susceptibility: An updated meta-analysis.Semantic proximity Read ↗

Investigating the genetic association between ERAP1 and ankylosing spondylitis.Semantic proximity Read ↗

A study of the association between single nucleotide polymorphisms of the endoplasmic reticulum aminopeptidase 2 (ERAP2) gene and the risk of ankylosing spondylitis in Egyptians.Semantic proximity Read ↗

ERAP1 is associated with ankylosing spondylitis in Han Chinese.Semantic proximity Read ↗

Association between ERAP1 gene polymorphisms and ankylosing spondylitis susceptibility in Han population.Semantic proximity Read ↗

Investigating the genetic association between ERAP1 and spondyloarthritis.Semantic proximity Read ↗

A polymorphism in ERAP1 is associated with susceptibility to ankylosing spondylitis in a Turkish population.Semantic proximity Read ↗

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