Article
Association of PTPN22 polymorphsims and ankylosing spondylitis susceptibility.
International journal of clinical and experimental pathology - 1 Jan 2015
Meng Qingxi, Zhang Xiaojun, Liu Xin, Wang Weiguo, Yu Peng, Shan Qunqun, Mao Zhaohu, Zhao Tingbao
Abstract excerpt
BACKGROUND: As a susceptibility gene for AS, the polymorphsims of PTPN22 associated with disease susceptibility. METHODS: We selected two SNPs of rs1217406 and rs1217414 within PTPN22 with Haploview software and investigated the relationship between the SNPs of PTPN22 gene and AS susceptibility. 120 AS patients and 100 healthy people were enrolled from Qilu Hospital of Shandong University. And we genotyped the...
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