Article
A family-based genome-wide association study reveals an association of spondyloarthritis with MAPK14.
Annals of the rheumatic diseases - 1 Jan 2017
Costantino Félicie, Talpin Alice, Said-Nahal Roula, Leboime Ariane, Zinovieva Elena, Zelenika Diana, Gut Ivo, Charon Céline, Izac Brigitte, Weissman Michael, Chiocchia Gilles, Reveille John, Breban Maxime, Garchon Henri-Jean
Abstract excerpt
OBJECTIVE: More than 40 loci have been associated with ankylosing spondylitis (AS), but less is known about genetic associations in spondyloarthritis (SpA) as a whole. We conducted a family-based genome-wide association study (GWAS) to identify new non-major histocompatibility complex (MHC) genetic factors associated with SpA. METHODS: 906 subjects from 156 French multiplex families, including 438 with SpA, were...
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