Article
Phenotype comparison of three acetylcholinesterase knockout strains.
Journal of molecular neuroscience : MN - 1 Jan 2006
Duysen Ellen G, Lockridge Oksana
Abstract excerpt
The phenotypes of three mouse strains that carry the acetylcholinesterase knockout (AChE KO) mutation have been compared. The AChE KO mouse was developed from embryonic stem (ES) cells, originating from a 129/Sv blastocyst. Animals generated from strain 129/Sv suffer from dysgenesis of the corpus callosum and possibly a number of other neuroanatomical deficiencies. To determine the contribution of background...
Topics
- Acetylcholinesterase
- Animals
- Body Temperature
- Body Weight
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Phenotype
